Rab6-interacting golgin

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August undefined, 2024

WebJan 14, 2009 · Comparison with the structure of Rab6 in complex with the human golgin protein GCC185 shows similarities in the nature of the Rab-effector interface and topology … WebJan 25, 2008 · As expected, Golgin-97 and Golgin-245 also lost Golgi association in Arl1 depleted cells , however global TGN organization remained intact as determined by TGN46 localization . Yet the Y1618A mutation did not completely abolish Golgi localization, from which we conclude that C-110 associates predominantly via Rab-binding domain …

GORAB golgin, RAB6 interacting - NIH Genetic Testing Registry …

WebIn recent years, a large number of coiled-coil proteins localised to the Golgi apparatus have been identified using antisera from human patients with a variety of autoimmune … Webgolgin, RAB6 相互作用：该基因编码 golgin 家族的一个成员，golgin 家族是一组定位于高尔基体的卷曲螺旋蛋白。编码的蛋白质可能在分泌途径中起作用。编码的蛋白质也定位于细胞质，通过与 N 末端激酶样蛋白质的相互作用而被鉴定，因此它可能在有丝分裂中发挥作用。 streaming final piala aff 2021

Rab6 and Rab11 Regulate Chlamydia trachomatis Development and Golgin …

WebOrthologous to human GORAB (golgin, RAB6 interacting). [provided by Alliance of Genome Resources, Apr 2024] Gorab golgin, RAB6-interacting [ (Norway rat)] Gene ID: 304923, updated on 5-Aug-2024. Summary. Predicted to be involved in non-motile cilium assembly. Predicted to act ... WebOct 29, 2024 · This section has been translated automatically. GORAB is the acronym for "Golgin RAB6-interacting" and refers to a gene encoding a protein of the same name, a member of the Golgin family, a group of coiled-coil proteins located in the Golgi apparatus. It interacts with small guanosine triphosphatases (RAB6) and plays an important role in … WebRAB6-interacting golgin. Gene. Gorab. Status. UniProtKB reviewed (Swiss-Prot) Organism. Rattus norvegicus (Rat) Amino acids. 368. Protein existence. Evidence at transcript level. Annotation score. 3/5. Entry. Feature viewer. ... PTHR21470 RAB6-INTERACTING PROTEIN GORAB 1 hit; Pfam. View protein in Pfam; streaming final destination 4 sub indo

A novel Rab6-interacting domain defines a family of Golgi-targeted …

(PDF) Structural Basis for Recruitment of Rab6-Interacting Protein …

Webco-workers, GFP-tagged Rab6 and Rab11 were shown to associate with C. trachomatis [28]. Detailed analysis demonstrated that Chlamydia expresses and secretes specific Rab binding proteins into the inclusion membrane, but the precise function of Rab interactions for Chlamydia remains elusive [29,30]. Here we show that Rab6A and Rab11A regulate ... WebPTHR21470:SF2 RAB6-INTERACTING GOLGIN 1 hit; PTHR21470 RAB6-INTERACTING PROTEIN GORAB 1 hit; Pfam. View protein in Pfam; PF04949 Transcrip_act 1 hit; MobiDB. streaming finale hommes 2021 wimbledonWebNov 1, 2024 · Second, Myosin II and RAB6 are found co-localized on peripheral dots with GCC185, a TGN Golgin known to recruit the MT + TIP CLASP proteins to the TGN, allowing the nucleation and formation of ... ro water purifier in palarivattom

"WebThis gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been … " - Rab6-interacting golgin

Rab6-interacting golgin

Rab6 and Rab11 Regulate Chlamydia trachomatis Development and Golgin …

This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi apparatus. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it … See more RAB6-interacting golgin also known as N-terminal kinase-like-binding protein 1 (NTKL-BP1) or SCY1-like 1-binding protein 1 (SCYL1-BP1) is a protein that in humans is encoded by the GORAB gene. See more Mutations in this gene have been associated with geroderma osteodysplastica. See more • Yan J, Di Y, Shi H, Rao H, Huo K (October 2010). "Overexpression of SCYL1-BP1 stabilizes functional p53 by suppressing MDM2-mediated ubiquitination". FEBS Letters. 584 (20): … See more • Gerodermia osteodysplastica See more • SCYL1BP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine See more WebRecently, the crystal structures of Rab6 in complexes with two unrelated effectors have been determined. The structure of Rab6a-GTP in complex with a 378-residue internal fragment of the effector Rab6IP1 (Rab6-interacting protein 1) has been solved. In addition, the structure of Rab6 with the golgin, GCC185, has also been determined.

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WebAug 22, 2024 · By interacting with Rab6, TMF also regulates retrograde membrane traffic from endosomes to the GA and from the Golgi to the ... SCYL1-Binding Protein 1; hNTKL-BP1; Golgin, RAB6 Interacting) GORAB is a coiled-coil membrane protein which localizes in trans-Golgi via a specific, GTP-dependent interaction with the small GTPases ARF5 and ... WebFeb 1, 2009 · Interactions with Rab6 are restricted to a1 and a8 of the RUN1 domain. The intervening helix a9 (residues 919-926) ... ison with the structure of Rab6 in complex with the human golgin.

WebDownload scientific diagram The Golgi-targeting motif of golgin, RAB6-interacting (GORAB) is found within amino acids 200 to 277 of the internal Golgi-targeting Rab6 and Arf5 binding domain ... WebApr 8, 1999 · The domain preferentially bound to Rab6 on protein blots, and mutations that abolished Golgi targeting resulted in a loss of this interaction. Sequence analysis revealed …

WebHere we demonstrate that gerodermia osteodysplastica is caused by loss-of-function mutations in SCYL1BP1, which is highly expressed in skin and osteoblasts. The protein … WebApr 8, 1999 · Interaction of golgin-97 and golgin-245 with Rab6 on farwestern blots. Golgin-97 was used to probe farwestern blots of Rab1, 2, 3a, 5, 6 and 11. (a) A quantitation of such a blot is shown together with an equivalent Coomassie-stained gel. (b) An autoradiograph of an experiment using Rab1 and Rab6 probed with golgin-97 and golgin-245.

WebRAB6-interacting golgin, N-terminal kinase-like-binding protein 1, NTKL-binding protein 1, SCY1-like 1 binding protein 1, SCYL1-binding protein 1. GeneRIFs: Gene References Into …

WebNational Center for Biotechnology Information ro water purifier in indiaWebThe golgin family consists of a group of coiled-coil proteins that play different roles in Golgi-related transport processes. The GORAB protein interacts with the GTP-bound form of the … streaming film yowis benWebFeb 5, 2024 · GORAB golgin, RAB6 interacting Gene ID: 92344 ... This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The … streaming final aff 2020WebNov 1, 2024 · Second, Myosin II and RAB6 are found co-localized on peripheral dots with GCC185, a TGN Golgin known to recruit the MT + TIP CLASP proteins to the TGN, allowing … streaming film zombie tidal wave sub indoWebgolgin, RAB6-interacting. Synonyms: Scyl1bp1, NTKL-BP1. Order Alleles. IMPC Data Collections. No Body Weight Data No Embryo Imaging Data No Viability Data IMPC Phenotype Summary ... ro water purifier in kochiWebNov 9, 2008 · The protein localizes to the Golgi apparatus and interacts with Rab6, identifying SCYL1BP1 as a golgin. ... caused by mutations in SCYL1BP1, a Rab-6 … streaming finale open australieWebAI467484; dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued; GO; golgin, RAB6 interacting; golgin, RAB6-interacting; Gorab; hNTKL-BP1; mNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKLBP1; NTKL-BP1; RAB6-interacting golgin; RAB6-interacting … streaming finance